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New Light on Causes of Severe Inflammation in COVID Patients’ Blood Vessels

A new pathway has been found whereby SARS-CoV-2 infects the endothelium cells – the innermost layer of the blood vessels, causing hyper inflammation, blood clotting and thrombosis in severe COVID-19 patients. In a collaborative research, a CU Medicine team has discovered that the virus induces inflammation by activating a unique cell surface receptor called (TLR) 4, without entering the host cell……